What Is Spravato?
Spravato is the brand name for intranasal esketamine, which has been FDA approved for the treatment of Depression. Among medications for Depression, it holds the rare distinction of being one from which patients can see immediate positive effects (sometimes as soon as within a day).
Is Esketamine Different from Ketamine?
Ketamine has long been used as an intravenous anesthetic. Ketamine unfortunately also has a reputation as a recreational drug, but it has legitimate medical uses under the direction of a physician.
Esketamine or “S Ketamine” is a form of ketamine, but it is delivered as a nasal spray instead of intravenously. The difference in how the drug is administered means that patients can receive each Spravato treatment less invasively—intranasally rather than intravenously.
Another important difference is that intravenous ketamine is not FDA-approved for the treatment of Depression, but the nasal spray esketamine is. For this reason, esketamine is usually covered by insurance plans, making it more financially accessible to patients.