Esketamine Spravato Treatment Center in Manhattan

Mid City TMS serves as a Spravato treatment center, offering esketamine nasal spray as an option for our patients.

What Is Spravato?

Spravato is the brand name for intranasal esketamine, which has been FDA approved for the treatment of Depression. Among medications for Depression, it holds the rare distinction of being one from which patients can see immediate positive effects (sometimes as soon as within a day). 

Is Esketamine Different from Ketamine?

Ketamine has long been used as an intravenous anesthetic. Ketamine unfortunately also has a reputation as a recreational drug, but it has legitimate medical uses under the direction of a physician.

Esketamine or “S Ketamine” is a form of ketamine, but it is delivered as a nasal spray instead of intravenously. The difference in how the drug is administered means that patients can receive each Spravato treatment less invasively—intranasally rather than intravenously.

Another important difference is that intravenous ketamine is not FDA-approved for the treatment of Depression, but the nasal spray esketamine is. For this reason, esketamine is usually covered by insurance plans, making it  more financially accessible to patients.


Who Is a Good Candidate for Esketamine Nasal Spray at a Spravato Treatment Center?

If you are suffering from Depression , it’s important to be aware of all of the treatment options available to you. Patients who have tried two or more antidepressant medications without sufficient improvement are often good candidates for esketamine treatment. If you suffer from treatment-resistant Depression, Mid City TMS can help you determine whether esketamine or another treatment, such as Transcranial Magnetic Stimulation (TMS), is the right next step for you.

What Will Your Appointment at Our Spravato Treatment Center Be Like?

This Spravato treatment center’s friendly staff will provide you with instructions and answer any questions to ensure that you feel fully prepared before, during, and after receiving Spravato treatments.  

Each Spravato treatment session involves monitoring for two hours in our office because of the potential acute side effects of the medication, which can include, among other effects, sedation and a feeling of disassociation.

You can expect to attend at least three sessions of Spravato treatment. After three sessions, if you are not seeing any benefits from the treatment, you and your provider may determine that it is time to change your treatment plan. If so, you may want to consider other options, such as TMS. However, if esketamine treatment is working for you, you may continue treatment for additional sessions, which are usually done twice a week for the first four weeks and then once a week for the second four weeks.  After this two month induction period, many patients continue maintenance sessions, usually done every two to three weeks.

Mid City TMS Can Help You Learn if Spravato is Right For You 

Figuring out which of the many Depression treatments currently available will improve your symptoms can feel overwhelming. With four years of experience as a New York City Spravato treatment center, Mid City TMS’ professionals can help you determine whether esketamine is a good fit for your Depression treatment. Medical Director Dr. Bryan Bruno is a psychiatrist who has over thirty years of experience treating Depression and will customize your treatment plan to your specific needs. Contact us to get started today.

Image of the interior of this Spravato treatment center, Mid City TMS

Contact Us

We are ready to help you feel better.
Get in touch with us and find out if Spravato is the best option for you.

Call us today. We can answer all of your questions.


280 Madison Ave, Suite 1102,
New York, NY 10016

[email protected]

Open Monday to Friday from 8:00 AM to 8:00 PM

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